Patients admitted to the Intensive Care Unit (ICU) are critically ill and require intensive care. Most ICU patients need mechanical ventilation to support their breathing. While this intervention saves many lives, it also carries risks. Those who remain on ventilation for extended periods are particularly vulnerable to adverse effects. How can we provide the best possible care for this fragile group of patients? The research group also focuses on two other key themes within ICU care: high workload and sustainability.