A systematic review of validated assessments methods for head and neck lymphedema

Coralie R. Arends, Josephine E. Lindhout, Lisette van der Molen, Erica A. Wilthagen, Michiel W.M. van den Brekel, Martijn M. Stuiver

Research output: Contribution to journalReview articleAcademicpeer-review

2 Downloads (Pure)



This systematic review aimed to provide a comprehensive overview of the validity and reliability of existing measurement instruments for quantifying head and neck lymphedema. 


Four databases were searched on January 31st, 2022. The COnsensus-based Standards for selecting health Measurement INstruments (COSMIN) checklists were used for the risk of bias (ROB) assessment. 


Out of 3362 unique records, eight studies examined the reliability and validity of five measurement instruments of which one patient reported outcome. The Patterson scale for internal lymphedema and the patient reported head and neck external lymphedema and fibrosis (LIDS-H&N) demonstrated validity and reliability. For external lymphedema, none of the instruments had good reliability for all measuring points.


There is a lack of sufficiently reliable and valid measurement instruments for external head and neck lymphedema. The Patterson scale and the patient reported LIDS-H&N seem reliable for clinical practice and research.

Original languageEnglish
Pages (from-to)2653-2661
JournalEuropean Archives of Oto-Rhino-Laryngology
Issue number6
Publication statusPublished - Jun 2023


Dive into the research topics of 'A systematic review of validated assessments methods for head and neck lymphedema'. Together they form a unique fingerprint.

Cite this