Additional effects of exercise to hypocaloric diet on body weight, body composition, glycaemic control, and cardio-respiratory fitness in adults with overweight or obesity and type 2 diabetes: a systematic review and meta-analysis

R.G. Memelink, M. Hummel, A. Hijlkema, M.T. Streppel, Ivan Bautmans, P.J.M. Weijs, Kirsten Berk, C.A.B. Tieland

Research output: Contribution to conferenceAbstractAcademic

Abstract

Aims: This systematic review and meta-analysis evaluates the additional effects of exercise to hypocaloric diet on body weight, body composition, glycaemic control, and cardio-respiratory fitness in adults with overweight or obesity and type 2 diabetes.
Methods: Embase, Medline, Web of Science, and Cochrane Central databases were evaluated and 11 studies were included. Random-effects meta-analysis was performed on body weight and measures of body composition and glycaemic control, to compare the effect of hypocaloric diet plus exercise with hypocaloric diet alone.
Results: Exercise interventions consisted of walking or jogging, cycle ergometer training, football training, or resistance training, and duration varied from 2 to 52 weeks. Body weight and measures of body composition and glycemic control decreased during both the combined intervention and hypocaloric diet alone. Mean difference in change of body weight (-0.77 kg [95% CI: -2.03; 0.50]), BMI (-0.34 kg/m2 [95% CI: -0.73; 0.05]), waist circumference (-1.42 cm [95% CI: -3.84; 1.00]), fat-free mass (-0.18 kg [95% CI: -0.52; 0.17]), fat mass (-1.61 kg [95% CI: -4.42; 1.19]), fasting glucose (+0.14 mmol/l [95% CI: -0.02; 0.30]), HbA1c (-0.06 % [95% CI: -0.25; 0.13]), and HOMA-IR (+0.01 [95% CI: -0.40; 0.42]) was not statistically different between the combined intervention and hypocaloric diet alone. Two studies reported VO2max and showed significant increases upon addition of exercise to hypocaloric diet.
Conclusions: Additional effects of exercise to hypocaloric diet in adults with overweight or obesity and type 2 diabetes were not shown for body weight, body composition, or glycaemic control, while cardio-respiratory fitness improves.
Original languageEnglish
Number of pages1
Publication statusPublished - Nov 2022
EventAnnual Dutch Diabetes Research Meeting 2022 - Wageningen, Netherlands
Duration: 3 Nov 20224 Nov 2022
https://www.addrm.online/

Conference

ConferenceAnnual Dutch Diabetes Research Meeting 2022
Abbreviated titleADDRM 2022
Country/TerritoryNetherlands
CityWageningen
Period3/11/224/11/22
Internet address

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