Effect of proactive pharmacist participation on medication errors in a paediatric intensive care unit

Marieke Tio, Jolanda Maaskant, Hester Vermeulen, Vincent Geukers, Reinier Van Hest

Research output: Contribution to journalArticleProfessional

Abstract

OBJECTIVE To study the effect of structured medication review, followed by feedback, performed by a clinical pharmacist as part of the multidisciplinary team, on medication errors IME] in critically ill children. DESIGN Interrupted time series with six pre-intervention data collection points and six post-intervention data collection points. METHODS We expanded the multidisciplinary team, with a clinical pharmacist, who was available on the paediatric intensive care unit (PICU) for approximately 3 hours on workdays. The clinical pharmacist performed structured medication reviews and provided feedback to the paediatrician-intensivists and nurses during the ward rounds. We measured the prevalence of MEs by exploring the clinical records of the patients and the incident reporting system. If an ME was suspected, a paediatrician-intensivist and a clinical pharmacist determined causalityand preventability. Harm was classified according to the National Coordinating Council for Medication Error Reporting and Prevention categories. RESULTS We included 254 patients in the pre-intervention and 230 patients in the post-intervention period. We identified 153 MEs in the pre-intervention period, corresponding with 2.3 per 100 prescriptions, and 90 MEs in the post-intervention period, corresponding with 1.7 per 100 prescriptions. Autoregressive integrated moving average analyses revealed a significant change in slopes between the pre-intervention and post-intervention periods (β -0.21; CI95 -0.30- -0.04; P = 0.022). CONCLUSION The implementation of structured medication review, followed by feedback, by a clinical pharmacist as part of the multidisciplinary team, resulted in a significant reduction of MEs in a tertiary PICU.

Translated title of the contributionEffect of proactive pharmacist participation on medication errors in a paediatric intensive care unit
Original languageDutch
Pages (from-to)29-33
Number of pages5
JournalPharmaceutisch Weekblad
Volume151
Issue number24
Publication statusPublished - 17 Jun 2016
Externally publishedYes

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