Negative pressure wound therapy for patients with hard-to-heal wounds: A systematic review

Alexandra H.J. Janssen, Johannes A. Wegdam, Tammo S. De Vries Reilingh, Anne M. Eskes, Hester Vermeulen

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)


Objective: Despite the lack of evidence, negative pressure wound therapy (NPWT) is commonly used in patients with hard-to-heal wounds. In our medical centre, one third of patients with abdominal wounds infected postoperatively end this therapy prematurely due to negative experiences and prefer standard wound care. This study was designed to explore the effects of NPWT on quality of life (QoL). Method: A search from 2000 to 2019 in eight databases was performed to identify qualitative studies of patients treated with NPWT. Studies were selected by two independent reviewers, who appraised the methodological quality, extracted and structured the data and performed content analysis. Results: A total of fve qualitative studies with good methodological quality, incorporating 51 individual patients, were included. After content analysis, four major themes emerged: reduced freedom of movement caused by an electric device; decreased self-esteem; increased social and professional dependency; and gaining self-control. Conclusion: NPWT has major effects on the physical, psychological and social domains of QoL. Knowledge of these effects may lead to improved treatment decisions for patients with hard-to-heal wounds regarding use of NPWT or standard wound care.

Original languageEnglish
Pages (from-to)206-212
Number of pages7
JournalJournal of Wound Care
Issue number4
Publication statusPublished - 2 Apr 2020


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